The Yale Center for Molecular Discovery has contributed to the following publications by collaborating with Yale faculty.
Buckley, D.L.; Gustafson, J.L.; Van Molle, I.; Roth, A.G.; Tae, H.S.; Gareiss, P.C.; Jorgensen, W.L.; Ciulli, A.; Crews, C.M. Small-Molecule Inhibitors of the Interaction between the E3 Ligase VHL and HIF1α. Angewandte Chemie International Edition English, 2012, 51(46): 11463-11467.
Noblin, D.J.; Page, C.M.; Tae, H.S.; Gareiss, P.C.; Schneekloth, J.S.; Crews, C.M. A HaloTag-Based Small Molecule Microarray Screening Methodology with Increased Sensitivity and Multiplex Capabilities. ACS Chemical Biology, 2012: doi: 10.1021/cb300453k.
Woo, C.M.; Beizer, N.E.; Janso, J.E.; Herzon, S.B. Isolation of Lomaiviticins C–E, Transformation of Lomaiviticin C to Lomaiviticin A, Complete Structure Elucidation of Lomaiviticin A, and Structure–Activity Analyses.J. Am. Chem. Soc., 2012, 134 (37):15285–15288.
Gareiss PC, Schneekloth AR, Salcius MJ, Seo S-Y, Crews CM. Identification and Characterization of a Peptidic Ligand for Ras. ChemBioChem 2010; 11:517-22.
Goodwin, EC, Atwood, WJ, and DiMaio, D. High-throughput, cell-based screen for chemicals that inhibit infection by SV40 and human polyomaviruses. J. Virol 2009; 83:5630-5639.
Yi F, Zhu P, Southall N, Inglese J, Austin CP, Zheng W, Regan L. An AlphaScreen-Based High-Throughput Screen to Identify Inhibitors of Hsp90-Cochaperone Interaction. J Biomol Screen. 2009; 14: 273-81.
Rodriguez-Gonzalez A, Cyrus K, Salcius M, Kim K, Crews CM, Deshaies RJ, Sakamoto KM. Targeting steroid hormone receptors for ubiquitination and degradation in breast and prostate cancer. Oncogene. 2008 Dec 4;27(57):7201-11.
Lewis CA, Merkel J, Miller SJ. Catalytic site-selective synthesis and evaluation of a series of erythromycin analogs. Bioorg Med Chem Lett. 2008 Nov; 18(22):60007-6011.
Saunders LP, Ouellette A, Bandle R, Chang WC, Zhou H, Misra RN, De La Cruz EM, Braddock DT. Identification of small-molecule inhibitors of autotaxin that inhibit melanoma cell migration and invasion. Mol Cancer Ther. 2008 Oct; 7(10):3352-3362.
Blount K, Puskarz I, Penchovsky R, Breaker R. Development and application of a high-throughput assay for glmS riboswitch activators. RNA Biol. 2006 Apr;3(2):77-81.