Congratulations Dr. Merkel on your new publication!

September 1, 2016

Working with external groups, YCMD optimized an enzymatic assay for soluble phospholipase A2 activity across 28 medically important snake venoms from six continents. Two related inhibitors were demonstrated to powerfully inhibit venoms displaying nanomolar and subnanomolar activity. Inhibitor testing preceded animal studies showing a survival benefit when the small molecule inhibitors were added before or after venom exposure. More…